By Prem Puri

This e-book is the prime foreign resource of reference at the surgical administration of neonatal issues. It presents a complete compendium of the pathophysiology, research and administration of those stipulations. approximately a hundred contributed chapters compile a distinct overseas consensus of specialist opinion. All sleek advancements together with advances in fetal surgical procedure are coated during this revised edition.
in addition to a complete replace all through, the second one variation contains a number of new chapters on ground-breaking advancements in neonatal surgical procedure. The authorship has been improved to usher in a couple of extra specialists.

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The cells obtained may be subjected to a variety of tests including karyotype, genetic probes, or enzyme analysis. Due to the high mitotic rate of the chorionic villus cells, results for karyotyping may be obtained in less than 24 hours. Disadvantages include diagnostic errors due to maternal decidual contamination or genetic mosaicism of the trophoblastic layer of the placenta. 8 BIOCHEMICAL MARKERS Maternal blood and amniotic fluid can be screened for the presence of various biochemical markers that indicate fetal disease.

Genetics 1954; 39:185. 9. Lenz W. Fragen aus der Praxis. :Dtsch Med, 1961; 86:25–55. 10. Ministry of Health Reports on Public Health and Medical Subjects No. 112. Deformities caused by thalidomide. London: HMSO, 1964. 11. Ambrose AM, Larson PS, Borcelleca JF et al. Toxicological studies on 2,4-dichlorophenyl-P-nitrophenyl ether. Toxicol Appl Pharmacol 1971; 19:263–75. 12. Tenbrinck R, Tibboel D, Gaillard JLJ et al. Experimentally induced congenital diaphragmatic hernia in rats. J Pediatr Surg 1990; 25:426–9.

46 In our recent series,45 all 25 fetuses with managed hydrops died expectantly. 47 In utero surgical decompression may reverse hydrops and allow sufficient lung growth to permit survival in severe cases. 45 In the CCAM category (134 fetuses) 13 fetuses with hydrops underwent fetal lobectomy, with resolution of hydrops and survival to birth in eight out of 13 (62%) cases. There were five intraoperative or postoperative deaths. In addition, six fetuses with large cystic masses underwent thoracoamniotic shunting and five survived.

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