By Henry P. Parkman, Richard W. McCallum
Gastroparesis is an more and more famous ailment. therapy may be tough end result of the a number of mechanisms for symptom creation. Gastroparesis: Pathophysiology, Presentation and therapy serves as a concise reference in this disease that permits clinicians to speedy entry and evaluation the mandatory info for treating and coping with sufferers with gastroparesis. each one bankruptcy is written by experts of their respective sector. the amount will permit the reader to raised comprehend all elements of this illness. The ebook offers present thoughts in a number of parts beginning with the epidemiology, scientific presentation and pathophysiology of gastroparesis. The usual historical past of sufferers is explored in addition to review of sufferers with suspected gastroparesis. This part comprises chapters on instant pill Motility, Electrogastrography and Antroduodenal Manometry. this crucial source concludes with an entire part on remedy together with nutritional, prokinetic, antiemetic, sensory, electrical stimulation, and surgical tools. New advancements comprise using gastric electrical stimulation for therapy, using SmartPill for analysis, and a couple of new brokers in improvement for this sickness. Gastroparesis: Pathophysiology, Presentation and remedy is definitely the right reference for gastroenterologists, and likewise for surgeons, endocrinologists, basic care physicians and nutritionists seeking to retain speed with the most recent details remedies for his or her sufferers.
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Extra info for Gastroparesis: Pathophysiology, Presentation and Treatment (Clinical Gastroenterology)
Sample text
The impairment of gastric emptying does not correlate WITH THE INTENSITY OF ABDOMINAL PAIN ;14, 17]. Persistent epigastric pain not related to meal ingestion should suggest epigastric pain syndrome of functional dyspepsia, rather than gastroparesis [18= )N PATIENTS WITH GASTROPARESIS THE PRESENCE OF ABDOMINAL pain predicts poor response to gastric electrical stimulator placement [19]. EARLY OF PATIENTS WITH GASTROPARESIS PRESENT WITH HEARTBURN ANDOR REGURGITATION AS THEIR chief complaints [24= )T IS ESSENTIAL TO OBTAIN A DETAILED HISTORY IN PATIENTS WHO ARE REFRACTORY TO PROTON PUMP INHIBITORS 4HE PRESENCE OF EFFORTLESS REGURGITATION OF undigested foods, nausea, postprandial distress, or early satiety should suggest the POSSIBILITY OF GASTROPARESIS AND THE DIAGNOSTIC EVALUATION SHOULD BE REDIRECTED &UNDOPLICATION SHOULD BE AVOIDED TO PREVENT POSTFUNDOPLICATION GAS
BLOAT SYNDROME Psychological Issues Associated with Gastroparesis It is important to consider the psychological state in patients with gastroparesis.
S IN IRRITABLE BOWEL SYNDROME AND FUNCTIONAL DYSPEPSIA PAST PHYSICAL AND SEXUAL ABUSE MAY BE PRESENT in some patients with gastroparesis [12= 0SYCHOLOGIC ISSUES SHOULD BE ADDRESSED AND APPROPRIATE PHARMACOLOGIC THERAPY AND CONSULTATION SHOULD BE INITIATED ESPECIALLY in patients with refractory gastroparesis. Predominant Symptom Presentation 4HE TERM hGASTROPARESIS v WHICH IMPLIES A PARALYZED STOMACH DOES NOT DESCRIBE the whole spectrum of this heterogeneous clinical syndrome. The severity of gastric emptying impairment does not correlate with the severity of symptoms.
Vazquez-Roque Keywords 'ASTROPARESIS s 'ASTRIC EMPTYING s 'ASTRIC ACCOMMODATION Introduction Gastric motor functions represent a complex series of events that are regulated by circulating blood glucose and hormones, such as the incretins, extrinsic neural control from the brain and spinal cord, the enteric nervous system, the interstitial cells of Cajal (ICC), smooth muscle cells, and locally released neurotransmitters. The normal function of the two major regions of the stomach, the fundus and antrum, depend on these neural and muscular mechanisms.