By D.F. Horrobin

Biochemistry is the research of the chemistry of dwelling organisms, of the ways that foodstuff is used to serve all of the many wants of the physique. Biochemistry is heavily hooked up with foodstuff, the examine of the categories and quantities of assorted fabrics required within the vitamin. Biochemistry can also be inextricably int~rtwined with endo­ crinology, the examine of hormones, for many of the hormones exert their activities by means of changing the behaviour of chemical reactions in the physique. The vital challenge in biochemistry is that of the availability of strength. power is required for a large number of reasons of which muscular task is the easiest recognized. strength is needed for digestion, and for the functioning of the kidney, the liver, the mind and all of the different organs within the physique. power is additionally crucial for the increase of the advanced natural molecules of which the physique is con­ structed. eventually, lots of the strength applied in the world comes from the solar. crops may be able to faucet this power resource without delay by means of the method of photosynthesis. through the use of pigments, significantly the fairway chlorophyll, crops can seize the power of sun and use it to accumulate complicated ingredients comparable to fats, carbohydrate, protein and nucleic acids. the one uncooked fabrics required are carbon dioxide, water and straightforward inorganic ingredients corresponding to nitrates that are extracted from the soil.

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Essential Biochemistry, Endocrinology and Nutrition

Biochemistry is the examine of the chemistry of dwelling organisms, of the ways that nutrients is used to serve all of the many wants of the physique. Biochemistry is heavily hooked up with nutrients, the learn of the categories and quantities of assorted fabrics required within the nutrition. Biochemistry is usually inextricably int~rtwined with endo­ crinology, the examine of hormones, for many of the hormones exert their activities through changing the behaviour of chemical reactions in the physique.

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They are very widely distributed and a natural deficiency is most unlikely except possibly in those who over a very long period are incapable of absorbing fat. The main effects of deficiency which have been studied in animals and man are infertility in both sexes, muscle weakness and anaemia. There is no evidence that human infertility is ever due to vitamin E deficiency. 9 Nutrition In designing a good diet, at least four major problems must be dealt with. 1. Sufficient water must be provided daily.

Folic acid This is essential for the manufacture of nucleic acids and so is particularly required when cell division and protein synthesis are occurring rapidly. It is widely distributed in the food but much is made in the gut itself by the resident bacterial colony. It is particularly required by the skin and the lining of the gut, by the marrow manufacturing red cells and by the pregnant mother acting as host for the growth of a new child. Deficiencies are most likely to occur 54 THE VITAMINS in infancy, before the normal bacterial colony has been established, and in pregnancy when requirements are very high.

The fourth is primarily a problem met with in the developed countries. Calorific requirement and metabolic rate The numbers of calories released by pure samples of the various types of food can be measured by burning a known weight of the food in a device known as a bomb calorimeter. It has been demonstrated that when food is burned in such a device it releases precisely 10 .. , E ·co ]. "fi -e.. , u '>' .. ~ c: W u 5 ~t~~~I o~ ~~ ~~I~I _ _ ~Ul l ____ ____ _ __ __ Fig. 1. The relative amounts of energy which are freed by the burning of 1 g of fat, 1 g of carbohydrate and 1 g of protein.

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