By American Chemical Society
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Additional info for Chemical Factors in Hypertension: A collection of papers and discussion presented at the Symposium on Chemical Factors in Hypertension - 115th Ntl. Mtg. San Francisco, March 28 to April 1, 1949 (Advances in Chemistry Series)
Sample text
Palmer, R. , J. Am. Med. , 134, 9-14 (1947). Patton, H . , Page, E. , and Ogden, E . , Gynecol. , 76, 493-7 (1943). Peet, M . M . , and Isberg, E . M . , J. Am. Med. , 130, 467-73 (1946). Poppen, J . L . , 134, 1-9 (1947). Prinzmetal, M . , J. Clin. , 15, 63-83 (1936). Reed, R. , Sapirstein, L . , Southard, F . , Am. J. , 141, 70712 (1944). Rothlin, E . , Bull. Schweiz. Akad. med. , 2, 249-73 (1947). Sapirstein, L . , and Reed, R. , Proc. Soc. Exptl. Biol. , 57, 135-6 (1944). Selye, H . , and Stone, H .
Biosynthesis and Metabolism of Phenylethyl (Pressor) Amines KARL H. , Glenolden, Pa. This report presents the likely pathways in the bio synthesis of phenylethyl (pressor) amines from their amino acid precursors, discusses the relative signifi cance of the various modes b y which they may b e inactivated in the b o d y , and considers the interplay of these factors as they may relate to hypertension. Γhysiologically, hypertension may be defined as a n elevation of blood pressure above the normal limits of variability.
E v e n a massive dose of Priscoline taken with suicidal intent caused no lowering of blood pressure (67). Indeed Priscoline may actually cause an alarming increase in blood pressure in some patients (8). Summary T h e role of adrenergic blockade in the therapy of hypertension is still obscure. " Such agents are very effective i n lowering the blood pressure i n cases of neurogenic (sympatho-adrenal) hypertension. A t the present time, pheochromocytoma and intracranial lesions are the only causes of human hypertension which are definitely known to involve overactivity of the sympatho-adrenal system.