By Editors: Ernesto Carafoli and Marisa Brini

Authors spotlight a number of promising discoveries within the box of calcium signaling that offer new information regarding either genetic and purchased pathologies. Their discussions provide you with new insights into the underlying explanations of congenital and bought illnesses and aspect how to new, much more promising examine and cures.

Show description

Read or Download Calcium Signalling and Disease - Molecular Pathology of Calcium - Subcellular Biochemistry Vol 45 PDF

Best chemistry books

Marijuana Chemistry: Genetics, Processing, Potency (2nd Edition)

Describes the psychoactive parts of hashish and the results on efficiency of development stipulations, genetics, harvesting thoughts, and processing. comprises diversifications in THC and CBD content material, species differentiation, seeds, grafting, cloning, bonsai marijuana, transforming into ideas, extraction of THC, instruction of cannabis and hash oil, smoking vs consuming, checking out for THC and CBD, in addition to criminal matters.

Trace Element Analysis in Biological Specimens

The key subject matter of this booklet is analytical ways to track steel and speciation research in organic specimens. The emphasis is at the trustworthy choice of a couple of toxicologically and environmentally vital metals. it's basically a guide in response to the sensible event of every person writer.

Chemistry of Coal Conversion

The impetus for this ebook is twofold. First, in keeping with the good­ documented oil shocks of the Seventies there arose a resurgence of study job within the man made fuels sector. This publication makes an attempt to seize a number of the cutting edge advances that have been remodeled the previous decade within the zone of the chemistry of coal conversion.

Physics, chemistry and applications of nanostructures : proceedings of international conferences Nanomeeting 2011 : reviews and short notes, Minsk, Belarus, 24 - 27 May 2011

This publication offers invited reports and unique brief notes of modern effects received in experiences about the fabrication and alertness of nanostructures, which carry nice promise for the recent new release of digital and optoelectronic units. Governing fascinating and comparatively new issues equivalent to fast-progressing nanoelectronics and optoelectronics, molecular electronics and spintronics, nanophotonics, nanosensorics and nanobiology in addition to nanotechnology and quantum processing of knowledge, this publication supplies readers a extra whole figuring out of the sensible makes use of of nanotechnology and nanostructures.

Extra resources for Calcium Signalling and Disease - Molecular Pathology of Calcium - Subcellular Biochemistry Vol 45

Example text

Histological analysis of these animals revealed no significant abnormalities and no change in tumour susceptibility. No up-regulation at either an mRNA or protein level of annexins 1, 2, 4, 5, 6 or 11 was observed in brain, heart, liver and skeletal muscle, indicating there was no compensation by other members of the annexin protein family. The observed differences in the phenotypes of the two mice have been attributed to the different strategies used to knock-out the annexin 7 gene. Another case involves annexin 6.

Steinberg, 2005, Genetic dissection and prognostic modeling of a complex trait: overt stroke in sickle cell anemia. Nat Genet. 37: 435–440. A. Gornbein, 2005, Loss of annexin A1 expression in human breast cancer detected by multiple high-throughput analyses. Biochem Biophys Res Commun. 326(1): 218–27. , and D. Li, 2004, Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry.

Schrader, J. & Schwinger, R. H. (2005) J. Mol. Cell Cardiol. 38, 607–615. P. Rodrigo, 2004, Annexin A1 down-regulation in head and neck cancer is associated with epithelial differentiation status. Am J Pathol. 164(1): 73–9. , Creutz, C. , and S. E. Moss, 2005, Annexins: Linking Ca2+ signalling to membrane dynamics. Nat. Rev. 6: 449–461. , and F. Dumas, 2001, Actin and annexins I and II are among the main endothelial plasmalemma-associated proteins forming early glucose adducts in experimental diabetes.

Download PDF sample

Rated 4.43 of 5 – based on 20 votes