By Jerome F. Strauss III MD PhD, Robert L. Barbieri MD
Completely revised and now more desirable with colour paintings, the hot variation of this most well known reference keeps to supply the newest details at the prognosis and administration of reproductive endocrine issues. nationwide and foreign leaders from the sector of reproductive endocrinology-including 30 new authors-equip you with insurance that encompasses the total spectrum of reproductive pathophysiology and issues, from being pregnant and start to reproductive getting older. Full-color illustrations and new drawings supply a real-life depiction of simple phone buildings and endocrine responses for a greater realizing of the cloth, whereas new chapters discover the problems shaping modern perform. As knowledgeable seek advice name, it comprises handy on-line entry to the total textual content of the book-fully searchable-along with all the photographs, and references associated with Medline at www.expertconsult.com.
- Covers the total spectrum of reproductive pathophysiology and issues, from being pregnant and delivery to reproductive getting older.
- Includes the paintings of leaders within the box of reproductive endocrinology for counsel you could trust.
- Features each time, at any place on-line entry to the full textual content of the book-fully searchable-as good as all the pictures, and references associated with Medline.
- Offers new content material on renovation of fertility, endocrine disturbances affecting copy, imaging applied sciences, and adolescent reproductive endocrinology that discover the problems shaping modern-day practice.
- Includes full-color illustrations and new drawings which supply a real-life depiction of anatomy and telephone functionality and disorder for a better understanding.
- Provides a listing of prompt readings on the finish of every bankruptcy for additional reference.
- Presents clean insights into modern day box and destiny advances, in addition to a better overseas point of view.
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Extra info for Yen & Jaffe's Reproductive Endocrinology: Expert Consult - Online and Print, 6e
Sample text
Metabolism, Stress, and Reproduction194 METABOLIC STRESSES THAT INFLUENCE REPRODUCTION Caloric Restriction Reproduction is energetically taxing. Darwin wrote extensively about the effect of nutrition on fertility in sheep and other animals, observing that ewes feeding on lush lowland pastures were more fertile (and more likely to bear twins) than those grazing on sparse high ground. Indeed, the phenomenon of seasonal breeding—which is characteristic of most nonequatorial mammals—reflects the effect of seasonal food availability on reproductive success.
These hormones (and fuels, such as fatty acids) are believed to serve as satiety factors to reflect fuel status and thereby serve as one limb of the control system to regulate fuel homeostasis and body weight. They accomplish this task by acting on specific target cells in the brain that act as a complex neural circuit that coordinates energy regulation, metabolism, and feeding behavior. These same hormones are believed to provide signals to the neuroendocrine reproductive axis, allowing reproduction to proceed when fuel reserves are adequate, but inhibiting reproduction if reserves are too low to support the energy demands of reproduction.
There is compelling evidence to indicate that insulin is one critical signal to the neuroendocrine reproductive axis. Plasma levels of insulin increase and decrease as 80 60 40 Progesterone (ng/mL) 20 15 10 5 Food (Kcal) Distance (miles/day) 10 6 2 600 300 May Jul Sep Nov Jan Mar Figure 1-17. Effects of exercise and supplemental nutrition on menstrual cyclicity in the monkey. LH, luteinizing hormone. (From Williams NI, Caston-Balderrama AL, Helmreich DL, et al. Longitudinal changes in reproductive hormones and menstrual cyclicity in cynomolgus monkeys during strenuous exercise training: Abrupt transition to exercise-induced amenorrhea.