By Emmanuel Mignot (auth.), Meeta Goswami, S. R. Pandi-Perumal, Michael J. Thorpy (eds.)

This interdisciplinary quantity brings jointly the various world’s prime clinicians and researchers to debate present and expected advancements within the figuring out of narcolepsy.

The quantity is commonly divided into 4 major sections: part I: Etiology; part II: medical concerns; part III: Psychosocial issues; and part IV: administration. The components coated comprise findings from examine investigations at the genetic predisposition and pathophysiology, psychosocial features, and medical administration of narcolepsy via pharmacological and non-pharmacological equipment. precise consciousness is paid to the translational facets of narcolepsy.

This quantity is appropriate for sleep issues experts and researchers, psychiatrists, neurologists, psychologists, social employees, behavioral scientists, graduate scientific scholars, and any pros and researchers attracted to the interdisciplinary quarter of sleep drugs.

Key Features

· concentrate on matters confronted in day by day scientific settings – is helping to notify and alter medical practice

· Chapters deal with either scientific and learn foundation – highlights power components of destiny research

· Interdisciplinary and translational strategy – compatible for a variety of clinicians and biomedical professionals

Meeta Goswami, BDS, PhD, MPH, has been the director of the Narcolepsy Institute when you consider that its inception in 1985 and serves as an Assistant Professor of Neurology, Albert Einstein collage of medication. Her basic sector of study curiosity comprises narcolepsy and psychosocial issues.

S.R. Pandi-Perumal, M.Sc, is the President and leader government Officer of Somnogen Inc, a brand new York company. he's a familiar sleep researcher either nationally and the world over, and has authored many guides. His basic sector of study curiosity contains sleep and organic rhythms. he's a well known editor within the box of sleep drugs and has edited over 15 volumes facing quite a few sleep-related topics.

Michael J Thorpy, MD, has gained many awards for his study together with one of many sleep field's maximum honors: the Nathaniel Kleitman Award. he's a well-published researcher and a board-certified sleep health practitioner. He serves as a Professor of Neurology at Albert Einstein collage of drugs and the Director of the Sleep-Wake issues middle at Montefiore scientific middle, Bronx, long island.

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Extra resources for Narcolepsy: A Clinical Guide

Sample text

Kaufmann C, Schuld A, Pollmacher T, Auer DP. Reduced cortical gray matter in narcolepsy: preliminary findings with voxel-based morphometry. Neurology 2002;58(12):1852–5. 19 80. Draganski B, Geisler P, Hajak G, et al. Hypothalamic gray matter changes in narcoleptic patients. Nat Med 2002; 8(11):1186–8. 81. Overeem S, Steens SC, Good CD, et al. Voxel-based morphometry in hypocretin-deficient narcolepsy. Sleep 2003; 26(1):44–6. 82. Scammell TE. The frustrating and mostly fruitless search for an autoimmune cause of narcolepsy.

Sleep Res Online 1979;8:191. 19. Mignot E, Hayduk R, Black J, Grumet FC, Guilleminault C. HLA DQB1*0602 is associated with cataplexy in 509 narcoleptic patients. Sleep 1997;20(11):1012–20. 20. Mignot E, Lin L, Finn L, et al. Correlates of sleep-onset REM periods during the Multiple Sleep Latency Test in community adults. Brain 2006;129(Pt 6):1609–23. 21. Singh M, Drake CL, Roth T. The prevalence of multiple sleep-onset REM periods in a population-based sample. Sleep 2006;29(7):890–5. Bishop C, Rosenthal L, Helmus T, Roehrs T, Roth T.

The dog was then transferred to Stanford in 1974 where behavioral, EEG/EMG recordings, and pharmacology confirmed the diagnosis [15]. Press reports of these findings quickly led the owners of other canine narcoleptics to contact the Stanford clinic. Several dogs were then transferred to Stanford to begin a colony in 1975, and the first puppies were born in 1976. This breeding resulted in two strains of dog with inherited narcolepsy, Doberman pinschers and Labrador retrievers. In other breeds such as the toy poodle and the beagle, in which breeding was also begun, the disorder appeared to be only sporadic [16].

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