By Mauro Zonta
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16 In recent years, our laboratory has investigated the ability of a series of isothiocyanate compounds to inhibit NMBA-tumorigenesis in the rat esophagus. 17 PEITC is a primary product ofthioglucosidase-catalyzed hydrolysis of gluconasturtiin, a glucosinolate found in many cruciferous vegetables such as cabbage, Brussels sprouts, cauliflower, turnips, etc. 18 ,19 Previous studies in other laboratories have demonstrated the ability of PEITC to inhibit the metabolism and DNA methylation of a series of nitrosamine carcinogens both in vivo and in vitro.
Stoner and M. A. Morse 2. A. Carcinogen in a Transkeian Bantu food additive, Nature, 222: 1198 (1969). 3. P. S. Some aspects of the epidemiology and etiology of esophageal cancer with particular emphasis on the Transkei, South Africa, Adv. , 17: 18-229 (1973). 4. S. Research on esophageal cancer in China: a review. , 40: 2633 (1980). 5. S. Oesophageal cancer and alcohol consumption: importance of type of beverage, Int. J. Cancer, 23:443 (1979). 6. , and Kowalski, B. Intake of volatile nitrosamines from consumption ofa1cohols, J.
The term "green tea" relates to its manufacturing from fresh tea leaves and the bud of the plant by steaming or drying at elevated temperatures with the precaution to avoid oxidation of the polyphenolic compounds which mainly include epicatechins, the flavonol skeleton. 5 million metric tons), about 20% is green tea which is mainly consumed in Asian countries like Japan, China, Korea and India; about 0X OH OH a OH OH EC OH OH a OM HO I : OH HO OH ECG P= OH OH OH OM EGC OH OH o OH HO I a OH HO OM OM EGCG OM Silybin Figure 1.