By Mitsuo Kusano, Norihiro Kokudo, Masakazu Toi, Masaki Kaibori

This e-book offers a entire evaluate and outlook for the way forward for indocyanine eco-friendly (ICG) fluorescence navigation surgical procedure, that's attracting scientific curiosity as a secure and no more invasive technique not just in detecting cerebral vessels, coronary arteries, and biliary timber, but in addition in deciding upon sentinel lymph nodes in melanoma. The booklet begins with the features of ICG and photodynamic cameras/endoscopes, by means of designated descriptions of the purposes of ICG fluorescence imaging in numerous parts corresponding to ocular surgical procedure, neurosurgery, cardiovascular surgical procedure, and cosmetic surgery. It additionally covers choosing sentinel lymph nodes in breast melanoma in addition to cancers of the gastrointestinal tract, and gives useful details for hepato-biliary-pancreatic surgeons, equivalent to picking tattooing of liver segments and bile leakage. Written completely by way of specialists of their respective parts, ICG Fluorescence Imaging and Navigation Surgery bargains a necessary source for surgeons working on cancers and vascular problems within the mind and cardiovascular platforms and in plastic surgery.

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Example text

C) Operative views through the microscope after CEA. (d) ICG-VAG image after CEA shows good intensity of ICG fluorescence at the carotid bifurcation (arrow), but the cotton and the blood obscured the fluorescence intensity in the artery (arrowheads). (e, f) Flow 800 analysis showing the time–intensity curves at the plotted areas demonstrates the improvement of blood flow at the area plaque located (plotted areas 2, green; 5, light blue) plaque. 5 mg of ICG and 5 ml of distilled water as a single injection to visualize ICA blood stream [35, 36].

Dashti R, Laakso A, Niemela¨ M et al (2009) Microscope-integrated near-infrared indocyanine green videoangiography during surgery of intracranial aneurysms: the Helsinki experience. Surg Neurol 71(5):543–50 29. Roessler K, Krawagna M, Dorfler A et al (2014) Essentials in intraoperative indocyanine green videoangiography assessment for intracranial aneurysm surgery: conclusions from 295 consecutively clipped aneurysms and review of the literature. Neurosurg Focus 36, E7 30. G. technology: first application during intracranial aneurysm surgery.

When a similar dilution procedure is used in vivo, the highest ICG FI could be obtained. In our preliminary clinical trial using an injection into the palm of lymphedema patients, there was no difference in FI values between the ICG original solution and the 100-fold-diluted solution (Fig. 8). Our search for the optimal concentration for the highest ICG fluorescence intensity in plasma, with or without bovine albumin added, showed the maximum ICG fluorescence intensity when the stock solution was diluted 90-fold from an 80-fold solution (Fig.

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