By Nathan Ralph Gotthoffer

This publication initially written in 1945, has been newly edited by means of nice Lakes Gelatin corporation and is meant as a resume of the various researches, that have been made to figure out the worth of gelatin in meals and in drugs. Its goal is to deliver to the eye of the clinical occupation, and especially to the energetic study employee, the numerous position occupied via gelatin within the clinical literature of the world.

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Clin. N. , 83, 571, 2003. 14. D. , The isoprostanes: unique prostaglandin-like products of freeradical initiated lipid peroxidation, Drug Metab. , 31, 117, 1999. 15. Seppä, H. , Platelet derived growth factor chemotactic for fibroblasts, J. Cell. , 92, 584, 1982. 16. E. , Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor-, J. Exp. , 165, 251, 1987. 17. M. , CRC Press, Boca Raton, FL, 1992, chap. 2, p. 1. 18. , CRC Press, Boca Raton, FL, 1988, p. 139. 19.

Skin cells are glucose dependent for energy in cutaneous wound healing (3). Although adequate glucose levels are vital for wound healing, excessively high levels (hyperglycemia) have a negative impact on this process. CARBOHYDRATE REQUIREMENTS/ENERGY METABOLISM In healthy adults, carbohydrate intake should account for 45 to 60% of total consumed calories. Carbohydrate requirements for patients with burn injuries greater than 25% of the body surface area have been recommended at levels up to 60 to 65% of total energy requirement (4,5).

Obese patients have also been shown to have a higher incidence of surgical wound dehiscence, possibly because their operations can be more technically difficult, and they are prone to hematoma formation (41). Clearly, prevention of obesity is key; however, practitioners should be aware of the effects of obesity on wound healing. Excessive quantities of carbohydrates can also have a negative impact in the hospital setting. Even moderate degrees of hyperglycemia may result in an increased incidence of infection and adverse outcomes (42).

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