By Martin Frith, Christian Nørgaard Storm Pedersen

This booklet constitutes the refereed court cases of the sixteenth overseas Workshop on Algorithms in Bioinformatics, WABI 2016, held in Aarhus, Denmark. The 25 complete papers including 2 invited talks awarded have been conscientiously reviewed and chosen from fifty four submissions.
The chosen papers disguise quite a lot of themes from networks, tophylogenetic reports, series and genome research, comparative genomics, and mass spectrometry info research.

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Extra resources for Algorithms in Bioinformatics: 16th International Workshop, WABI 2016, Aarhus, Denmark, August 22-24, 2016. Proceedings

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4 Conclusions and Discussion We presented a novel algorithm for the connected maximum coverage problem, previously proposed for finding frequently mutated subnetworks in cancer. Our algorithm is based on an ILP formulation solved in a branch and cut framework. Our results show that our algorithm identifies subnetworks more frequently mutated and of higher statistical significance compared to previously proposed algorithms and to greedy approaches, while maintaining a runtime lower than or comparable to the runtime of greedy approaches.

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