By Jean-Pierre Despres, Vincenzo Di Marzo

This across the world popular writer crew offers a different and thorough research and distillation of the endocannabinoid approach and its dating to stomach weight problems, diabetes, and heart problems. The endocannabinoid approach (ECS) performs an enormous function in cardiometabolic hazard, in addition to modulating power stability, feeding habit, hepatic lipogenesis, and maybe glucose homeostasis. facts means that the ECS is overactive in human weight problems and dyslipidemia. severe to the administration of cardiometabolic danger, this new, well timed publication offers useful overviews and administration counsel on many vital issues, together with: belly weight problems and the metabolic syndrome the endocannabinoid process and effort stability: services and dysfunctions stomach weight problems, the EC procedure, and cardiometabolic danger

Show description

Read or Download Abdominal Obesity and the Endocannabinoid System: From Basic Aspects to Clinical Management of Related Cardiometabolic Risk PDF

Best endocrinology & metabolism books

Obesity and Diabetes (Practical Diabetes)

Style 2 diabetes, linked to weight problems, is this day the commonest type of diabetes. В it's also linked to a few different cardiovascular chance elements which represent the metabolic syndrome. В powerful administration of diabesity is essential to the aid of morbidity and untimely morbidity as a result of heart problems.

Essential Biochemistry, Endocrinology and Nutrition

Biochemistry is the research of the chemistry of residing organisms, of the ways that meals is used to serve the entire many wants of the physique. Biochemistry is heavily hooked up with nutrients, the learn of the categories and quantities of assorted fabrics required within the vitamin. Biochemistry can be inextricably int~rtwined with endo­ crinology, the examine of hormones, for many of the hormones exert their activities by way of changing the behaviour of chemical reactions in the physique.

Additional info for Abdominal Obesity and the Endocannabinoid System: From Basic Aspects to Clinical Management of Related Cardiometabolic Risk

Example text

Insulin resistance in microalbuminuric hypertension sites and mechanisms. Hypertension 1995; 26:789–795. 22. Natali A, Taddei S, Quinones Ga, et al. Insulin sensitivity, vascular reactivity, and clamp-induced vasodilatation in essential hypertension. Circulation 1997; 96:849–855. 23. Baron Ad, Brechtel-Hook G, Johnson A, et al. Skeletal muscle blood flow. A possible link between insulin resistance and blood pressure. Hypertension 1993; 21:129–135. 24. Hulthen Ul, Endre T, Mattiasson I, et al. Insulin and forearm vasodilation in hypertension-prone men.

Relative contribution of obesity and body fat distribution to alterations in glucose insulin homeostasis: Predictive values of selected indices in premenopausal women. Am J Clin Nutr 1989; 49(5):758–764. 26. Pouliot MC, Despr´es JP, Nadeau A, et al. Associations between regional body fat distribution, fasting plasma free fatty acid levels and glucose tolerance in premenopausal women. Int J Obes 1990; 14(4):293–302. 27. Pouliot MC, Despr´es JP, Nadeau A, et al. Visceral obesity in men. Associations with glucose tolerance, plasma insulin, and lipoprotein levels.

1), clearly indicates that the contribution of this depot to free fatty acid (FFA) release and turnover is quite small. Additionally, there is no convincing evidence in human that the portal FFA levels are higher than the systemic levels. Thus, if it is not through an augmentic lipolytic activity, how can an expanded visceral fat contribute the metabolic syndrome. Obviously, the view that visceral fat is only one, albeit clinically easily accessible, marker of ectopic fat deposition provides a credible answer since it is then also associated with ectopic fat deposition in other depots as well.

Download PDF sample

Rated 4.58 of 5 – based on 23 votes